Department of Biotechnology

Dr. K.H. Chandramouli, Lecturer Dr. K.H. Chandramouli
Educational Qualification Ph.D (Biochemistry), University of Mysore
Experience Teaching: 2 years
R&D: 8 years
Area of Interest Molecular Biology and Biofuels
Email ID khchandra@yahoo.com  

List of Publications:
Papers published in National and International Journals:
  1. Electrochemical and spectral analysis of oxidized products of 10-[3’Bis(hydroxyethyl) amino] propyl]-2-chlorophenoxazine redox indicator. B.C.Channu; K.H.Chandramouli; Ravi Hegde; S.G. Vadiraj;Y.C.Mayur and K.N.Thimmaiah. Asian Journal of Chemistry .Vol.14, No.1, pp1-15, 2002.
  2. Interaction of 2-Chloro-N10-substituted Phenoxazine with DNA and effect on DNA melting. K.H.Chandramouli; K.N.Thimmaiah; Arun Chandrashekar; Cletus J.M. D'Souza. Nucleosides ,Nucleotides & Nucleic acids. Vol 23, Issue 10 pp:1639 – 1656,2004.
  3. Sensitization of Multidrug Resistant (MDR) Cancer Cells to Vinblastine by Novel Acridones: Correlation between Anti-Calmodulin Activity and Anti-MDR Activity. Y.C. Mayur, T. Padma, B.H. Parimala, K.H. Chandramouli, S.Jagadeesh, N.M. Made Gowda and K.N. Thimmaiah. Medicinal Chemistry
    Vol 2, Issue 6, Pp.63-77, 2006
  4. Inhibition of Calmodulin-Dependent Cyclic AMP Phosphodiesterase by Phenoxazines. Shankar Jagadeesh, Thimmaiah Padma, Hanumesh Parimala,Yerigeri C.Mayur, K H. Chandramouli, Cletus J. M.
    D’Souza, and Kuntebommanahalli N. Thimmaiah. Biochemical and Biophysical Research Communications, 14, 342(3), 690-701, 2006.
  5. Breast cancer metastasis suppressor 1 (BRMS1) inhibits osteopontin transcription by abrogating NF-kappa B activation. Samant RS, Clark DW, Fillmore RA, Cieck.M, Metge BJ, Chandramouli KH, Chambers AF, Casey G, Welch DR,Shevde LA. Mol Cancer 2007 Jan 16; 6:6
  6. Loss of plasmid in plasmid carrying strains of Escherichia coli by 2-Fluoro-N10-substituted phenoxazines and their interaction with DNA. K.H. Chandramouli, Cletus J.M.D’Souza and K.N.Thimmaiah. Nucleosides Nucleotides Nucleic Acids. 2008;27(1):70-83.
  7. Identification of differentially expressed proteins in drug resistance cancer cells. K.H.Chandramouli, Kumaraguraguru Raja, K.N.Thimmaiah and Beeralli Seshi.Submitted to Proteome Science.July 2008.
National Conference:
  1. Decreased resistance to antibiotics and plasmid loss in plasmid carrying strains of Escherichia coli treated with substituted phenoxazines. Poster presented at XXth annual meeting of Indian Council for Chemists. University of Mysore. MYSORE, India. December 22 - 24 , 2001
  2. Loss of plasmids of Escherichia coli after treatment with substituted phenoxazines: National Seminar on Biotechnology-Challenges and prospects. Mangalore, India, January 4-6, 2002.
  3. Reversal of Drug Resistance in Cancer cells by Phenoxazine MDR Modulators: XXIst Annual Convention of the Indian association for cancer Research. Indian Institute of Science. BANGALORE, India. January 31-February 2, 2002.
  4. Interaction of N10-Substituted phenoxazines with DNA: Role of hydrophobicity and DNA Melting: Poster presentation at 71st Annual Meeting Society of Biological Chemists. Punjab Agricultural University. Ludhiana, India. November 14-16, 2002.
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